Medformin-500

Medformin 500

This medicine is prescription only medicine (POM ) and required under medical supervision .

ဤဆေးသည် POM ဆေးအုပ်စုတွင်ပါဝင်သောကြောင့် ဆရာဝန်ညွှန်ကြားချက်အတိုင်းသာ သုံးစွဲသင့်ပါသည် ။

Metformin is first-line drug of choice for the treatment of type 2 diabetes.

Action

- Decreases hyperglycemia primarily by suppressing glucose production by the liver (hepatic gluconeogenesis)

- Increases insulin sensitivity, enhances peripheral glucose uptake

- Decreases insulin-induced suppression of fatty acid oxidation

- Decreases absorption of glucose from the gastrointestinal tract.

Indications

Metformin is indicated in the control of type 2 diabetes mellitus i.e ,Non insulin dependent Diabetes Mellitus (NIDDM) especially in overweight patients. It can be given alone as initial therapy or as combination therapy with sulfonylurea.

Dosage

Adults : Initially, 500 or 850 mg BD or TDS during or after meals, gradually increase at intervals of at least 1 week according to response. Max: 3,000 mg daily in 3 divided doses. or Dosage directed by the physician.