Oardiance 25

Oardiance 25

This medicine is prescription only medicine (POM ) and required under medical supervision .

ဤဆေးသည် POM ဆေးအုပ်စုတွင်ပါဝင်သောကြောင့် ဆရာဝန်ညွှန်ကြားချက်အတိုင်းသာ သုံးစွဲသင့်ပါသည် ။

Description

Empagliflozin is a potent, selective, and reversible inhibitor of sodium-glucose co-transporter 2 (SGLT2), the main site of filtered glucose reabsorption in the renal proximal convoluted tubules. Inhibition of SGLT2 reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose resulting in increased urinary glucose excretion, thereby decreasing plasma glucose concentration.

Indications

Empagliflozin is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise: as monotherapy when metformin is considered inappropriate due to intolerance; in addition to other medicinal products for the treatment of diabetes

Dosage

As monotherapy (if metformin is inappropriate due to intolerance) or in combination with insulin or other antidiabetic agents in addition to diet and exercise to improve glycaemic control: Initially, 10 mg once daily in the morning, may be increased to 25 mg once daily if necessary and tolerated. Max: 25 mg daily.