Montefic Plus
- Category: ယားယံနှာမွှန်ပျောက်ဆေးများ
- UOM: Box of 10x10's Tablet
38,870 Kyats
Montefic Plus
This medicine is prescription only medicine (POM ) and it is required under medical supervision .
ဤဆေးသည် POM ဆေးအုပ်စုတွင်ပါဝင်သောကြောင့် ဆရာဝန်ညွှန်ကြားချက်အတိုင်းသာ သုံးစွဲသင့်ပါသည် ။
Description
Montelukast is a selective leukotriene receptor antagonist. It inhibits cysteinyl leukotriene type-1 (CysLT1) receptor found in the human airway and on other pro-inflammatory cells. The binding of CysLTs in leukotriene receptors is involved in the pathophysiology of asthma, including bronchoconstriction, mucous secretion, vascular permeability, and eosinophil recruitment. Additionally, CysLTs are released from the nasal mucosa after allergen exposure which is associated with symptoms of allergic rhinitis.
Levocetirizine, an antihistamine and is an active enantiomer of cetirizine. Its binding affinity to H1-receptor is twice than cetirizine. It selectively competes for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels and respiratory tract.
Indication
MONTEFIC PLUS is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis.
Dosage
Adults: One tablet containing Montelukast 5 mg and Levocetirizine 10 mg once daily or as prescribed by the physician.
| Montelukast | 5 mg |
| Levocetirizine | 10 mg |
Contraindications
MONTEFIC PLUS is contraindicated in patients with known hypersensitivity to Montelukast or Levocetirizine, patients with severe (creatinine clearance less than 10 ml/min) or hepatic impairment, in children 6-11 years of age with renal impairment, and women who are pregnant or breastfeeding.
Storage : Store below 30'C in a dry place. Protect from light and moisture.
