Medifumide

Medifumide

ဤဆေးသည် POM ဆေးအုပ်စုတွင်ပါဝင်သောကြောင့် ဆရာဝန်ညွှန်ကြားချက်အတိုင်းသာ သုံးစွဲသင့်ပါသည် ။
This medicine is prescription only medicine (POM ) and it is required under medical supervision .

Description

High-ceiling diuretic.Inhibit electrolyte and fluid reabsorption in the thick ascending limb of the Loop of Henle as well as in the proximal tubule. Approximately 90% protein bound.
The onset of diuresis following intravenous administration is within 5 minutes and  somewhat later after intramuscular administration. The peak effect occurs within the first half hour.The duration of diuretic effect is approximately 2 hours.

Indication
    - Cardiac oedema : All forms of cardiac oedema in conjunction with adequate glycoside  therapy.
    - Ascites due to cirrhosis of the liver, mechanical obstruction or cardiac failure.   
    - Renal oedema (in nephritic syndrome usually in conjunction with ACTH or corticosteroids).
    - Pulmonary oedema.
    - Forced diuresis e.g. management of barbiturate poisoning.   Burns: to reduce local oedema and prevent oliguria from progressing to complete anuria.

Dosage
    Intravenous or intramuscular administration of Furosemide is indicated in all cases where intestinal absorption is impaired or prompt diuresis is required.
    The rapid and powerful effect produced by intravenous injection may result in a transitory fall in plasma volume.
    Intravenous injection should be given slowly (over 1 to 2 minutes)
    The recommended adult dose by this route is 20 to 40 mg, repeated if necessary after not less than 2 hours.
    The usual pediatric dose is 1mg/kg.
    Pulmonary oedema : Initial dose 40 mg intravenously. If necessary, the injection may be repeated after approximately 60 to 90 minutes (or ) dosage directed by the physician